- Anti-wrinkle by rejuvenating skin by stimulating cell proliferation
- Minimizing pores
- Eliminating scars and speckles by improving the texture and condition of the skin
Obtained by genetic engineering technology (microbial recombinant) totally identical to natural EGF, known as a “BEAUTY FACTOR”, boosts and regulates stem cell proliferation. Because of its recombinant technology it is totally safe unlike other products that use human derived stem cells.
EGF (Human Oligopeptide-1 rh-EGF) is a growth factor that plays an important role in the regulation of cell growth, proliferation, differentiation and survival. It stimulates the synthesis of DNA, RNA, hydroxyproline as well as hyaluronic acid, accelerates cell proliferation and differentiation of various epidermal tissues, such as epidermis of skin, gastrointestinal tract and cornea.
The discovery of EGF won Stanley Cohen and Rita Levi-Motalcini a Nobel Prize in Physiology and Medicine in 1986.
EGF acts by binding with high affinity to epidermal growth factor receptors (EGFR) on the cell surface ultimately leading to DNA synthesis and cell proliferation.
EGF is a highly efficient cell division factor with a variety of biological activity. It can repair epidermis, delay aging, fade speckles, inhibit wrinkles, and moisten skin. The content of EGF in the body determines how old the skin is.
In younger people, the body can produce enough EGF to promote epidermal cell growth, but as we age, EGF production decreases gradually, and the renewal of epidermal cells markedly slows down. The deficiency of EGF will result in delayed wound healing, difficult scar healing, skin aging, and formation of wrinkles, freckles and age pigment.
Under these conditions, prompt supplement of EGF becomes extremely important. While natural, EGF is extraordinarily expensive and seldom can afford it. rh-EGF however, is a recombinant human epidermal growth factor obtained by genetic engineering technology. It is identical to EGF in human body so it can be used as an important supplement when body is in dire need of it.
The traditional method to minimize pores and reduce wrinkles has been to inject Botox. This in itself, has been found to cause severe side effects given the time it takes to reduce wrinkles. Botox can paralyze the nerves, and repeated injections cause muscle stiffness and loss of consciousness. It is also extremely expensive to administer. rh-EGF, however is inexpensive and has now become the first choice to eliminate wrinkles without the adverse reactions of Botox Injections.
Rh-EGF is suitable for individuals of any age and applicable to both men and women, especially for eyes and facial care.
EGF “Beauty Factor” in summary is widely used in skin care products with the following outcomes:
- Rejuvenates skin: EGF can help skin stem cells to absorb nutrients, speed cell metabolism, accelerate skin cell division and growth, and stimulate the synthesis of hyaluronic acid and glycoproteins.
- Accelerates cell regeneration and tissue repair: EGF can promote the healing of wound surface of skin and mucosa, reduce scar contracture and skin cell’s abnormal proliferation.
- Whiten skin: EGF can promote the growth of new cells which replace cells injured by ultraviolet radiation. It does this by reducing the number of melanocytes in the skin.
- J Drugs Dermatol. 2012 May;11(5):613-20. – Improved texture and appearance of human facial skin after daily topical application of barley produced, synthetic, human-like epidermal growth factor (EGF) serum
- J Cosmet Laser Ther. 2010 Feb;12(1):14-20. – Combination of physiologically balanced growth factors with antioxidants for reversal of facial photodamage
- Biol Cell. 2005 Mar;97(3):173-83. – Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing
- Lancet. 2001 Sep 29;358(9287):1067-8. – Dedifferentiation of epidermal cells to stem cells in vivo
- Mol Cell Biol. 1989 July p. 2771-2778 – Recombinant Human Epidermal Growth Factor Precursor Is a Glycosylated Membrane Protein with Biological Activity
- nobelprize.org – The Nobel Prize in Physiology or Medicine 1986