- Reduce and prevent fine lines and wrinkles by increasing synthesis of Collagen and Hyalurnic Acid
- Stimulates the synthesis of the key constituents of the skin matrix: collagen, elastin and glucosamnoglycans
- Nonirritating fall back option for people who develop skin irritation in response to retinoids or alpha-hydroxy acids
Palmitoyl Pentapeptide-4 is also known as Matrixyl is a pentapeptide, synethsized chain protein created by linking five amino acid peptides. Palmitoyl Pentapeptide-4 stimulates collagen and elastin fibroblasts, developing fibronectin (FN) and glycosaminoglycans (GAG). It became famous when research has shown that it is effective against wrinkles as retinol, but less irritating.
Independent in vitro studies demonstrated an increase in synthesis of Collagen I by 212%, Collagen IV by 100 to 327% and Hyaluronic Acid by 267%. Collagen I is predominant among the 19 forms of collagen found in the human body; therefore increasing production of Collagen I has a very dramatic effect on rebuilding the skin. Six month in vivo studies showed mean wrinkle depth was reduced by 17%, surface area containing deep wrinkles was reduced by 68%, surface area containing moderate wrinkles was reduced by 51% and skin roughness by 16%.
See also: Petides